protein a coated cm4 sensor chip Search Results


86
Biacore protein a coated cm4 sensor chip
Protein A Coated Cm4 Sensor Chip, supplied by Biacore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cytiva Europe cd3ε homodimer protein
Cd3ε Homodimer Protein, supplied by Cytiva Europe, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Sino Biological protein a
Protein A, supplied by Sino Biological, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cytiva Europe mabselect sure
Mabselect Sure, supplied by Cytiva Europe, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Becton Dickinson protein a/g
Protein A/G, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Sino Biological h02h extracellular domains
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Sino Biological human igg1 fc
Human Igg1 Fc, supplied by Sino Biological, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Pfizer Inc pdfixa
In vitro cofactor activity mechanism of NXT007. (A) Sensorgram of SPR analysis. NXT007, anti-FIX(a), or anti-FX monospecific one-armed antibody (BsAb containing one anti-FIX(a) or anti-FX arm, and one anti-KLH [keyhole limpet hemocyanin; nonmammalian origin protein] arm) were captured on the sensor tip, and the binding to rFIX, <t>pdFIXa,</t> pdFX, or pdFXa was detected. X-axis represents time (s) and Y-axis represents response unit. (B) Effect of NXT007, anti-FIX(a) or anti-FX monospecific one-armed antibodies on FIXa-catalyzed FX activation in an enzymatic assay using purified coagulation factors and phosphatidylserine-containing phospholipid. FIX, factor FIX; FIXa, activated factor IX; FX, factor X; FXa, activated factor X; pd, plasma-derived; <t>r,</t> <t>recombinant;</t> SPR, surface plasmon resonance.
Pdfixa, supplied by Pfizer Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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99
Cytiva Europe biacore
In vitro cofactor activity mechanism of NXT007. (A) Sensorgram of SPR analysis. NXT007, anti-FIX(a), or anti-FX monospecific one-armed antibody (BsAb containing one anti-FIX(a) or anti-FX arm, and one anti-KLH [keyhole limpet hemocyanin; nonmammalian origin protein] arm) were captured on the sensor tip, and the binding to rFIX, <t>pdFIXa,</t> pdFX, or pdFXa was detected. X-axis represents time (s) and Y-axis represents response unit. (B) Effect of NXT007, anti-FIX(a) or anti-FX monospecific one-armed antibodies on FIXa-catalyzed FX activation in an enzymatic assay using purified coagulation factors and phosphatidylserine-containing phospholipid. FIX, factor FIX; FIXa, activated factor IX; FX, factor X; FXa, activated factor X; pd, plasma-derived; <t>r,</t> <t>recombinant;</t> SPR, surface plasmon resonance.
Biacore, supplied by Cytiva Europe, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Becton Dickinson mouse anti-human igg kappa light chain
In vitro cofactor activity mechanism of NXT007. (A) Sensorgram of SPR analysis. NXT007, anti-FIX(a), or anti-FX monospecific one-armed antibody (BsAb containing one anti-FIX(a) or anti-FX arm, and one anti-KLH [keyhole limpet hemocyanin; nonmammalian origin protein] arm) were captured on the sensor tip, and the binding to rFIX, <t>pdFIXa,</t> pdFX, or pdFXa was detected. X-axis represents time (s) and Y-axis represents response unit. (B) Effect of NXT007, anti-FIX(a) or anti-FX monospecific one-armed antibodies on FIXa-catalyzed FX activation in an enzymatic assay using purified coagulation factors and phosphatidylserine-containing phospholipid. FIX, factor FIX; FIXa, activated factor IX; FX, factor X; FXa, activated factor X; pd, plasma-derived; <t>r,</t> <t>recombinant;</t> SPR, surface plasmon resonance.
Mouse Anti Human Igg Kappa Light Chain, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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86
Biacore sensor chip cm5
In vitro cofactor activity mechanism of NXT007. (A) Sensorgram of SPR analysis. NXT007, anti-FIX(a), or anti-FX monospecific one-armed antibody (BsAb containing one anti-FIX(a) or anti-FX arm, and one anti-KLH [keyhole limpet hemocyanin; nonmammalian origin protein] arm) were captured on the sensor tip, and the binding to rFIX, <t>pdFIXa,</t> pdFX, or pdFXa was detected. X-axis represents time (s) and Y-axis represents response unit. (B) Effect of NXT007, anti-FIX(a) or anti-FX monospecific one-armed antibodies on FIXa-catalyzed FX activation in an enzymatic assay using purified coagulation factors and phosphatidylserine-containing phospholipid. FIX, factor FIX; FIXa, activated factor IX; FX, factor X; FXa, activated factor X; pd, plasma-derived; <t>r,</t> <t>recombinant;</t> SPR, surface plasmon resonance.
Sensor Chip Cm5, supplied by Biacore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/protein+a+coated+cm4+sensor+chip/chip+cm5+sensor/10__1007_slash_978___1___4939___2877___4-4998-18-5
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Image Search Results


In vitro cofactor activity mechanism of NXT007. (A) Sensorgram of SPR analysis. NXT007, anti-FIX(a), or anti-FX monospecific one-armed antibody (BsAb containing one anti-FIX(a) or anti-FX arm, and one anti-KLH [keyhole limpet hemocyanin; nonmammalian origin protein] arm) were captured on the sensor tip, and the binding to rFIX, pdFIXa, pdFX, or pdFXa was detected. X-axis represents time (s) and Y-axis represents response unit. (B) Effect of NXT007, anti-FIX(a) or anti-FX monospecific one-armed antibodies on FIXa-catalyzed FX activation in an enzymatic assay using purified coagulation factors and phosphatidylserine-containing phospholipid. FIX, factor FIX; FIXa, activated factor IX; FX, factor X; FXa, activated factor X; pd, plasma-derived; r, recombinant; SPR, surface plasmon resonance.

Journal: Research and Practice in Thrombosis and Haemostasis

Article Title: NXT007 enhances in vitro coagulation potential in the coexistence of emicizumab in hemophilia A through distinct complex formation

doi: 10.1016/j.rpth.2025.103236

Figure Lengend Snippet: In vitro cofactor activity mechanism of NXT007. (A) Sensorgram of SPR analysis. NXT007, anti-FIX(a), or anti-FX monospecific one-armed antibody (BsAb containing one anti-FIX(a) or anti-FX arm, and one anti-KLH [keyhole limpet hemocyanin; nonmammalian origin protein] arm) were captured on the sensor tip, and the binding to rFIX, pdFIXa, pdFX, or pdFXa was detected. X-axis represents time (s) and Y-axis represents response unit. (B) Effect of NXT007, anti-FIX(a) or anti-FX monospecific one-armed antibodies on FIXa-catalyzed FX activation in an enzymatic assay using purified coagulation factors and phosphatidylserine-containing phospholipid. FIX, factor FIX; FIXa, activated factor IX; FX, factor X; FXa, activated factor X; pd, plasma-derived; r, recombinant; SPR, surface plasmon resonance.

Article Snippet: Each antibody was captured onto Sure Protein A (MabSelect SuRe) immobilized on a CM4 sensor chip (Cytiva), followed by injection of recombinant (r)FIX (Benefix; Pfizer), pdFIXa, pdFX, or pdFXa (Enzyme Research Laboratories) over the flow cells as described previously [ ].

Techniques: In Vitro, Activity Assay, Binding Assay, Activation Assay, Enzymatic Assay, Purification, Coagulation, Clinical Proteomics, Derivative Assay, Recombinant, SPR Assay